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ea0070aep373 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

The educational training to the Mediterranean diet-like pattern is followed by improvement in cardiometabolic parameters and ecology of the microbiome in children with obesity: Preliminary results of the GOOD DAY trial

Ricotti Roberta , Archero Francesca , Landoni Valentina , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Solito Arianna , Novello Giorgia , Gamalero Elisa , Mignone Flavio , Cavaletto Maria , Agosti Emanuela , Bona Elisa , Prodam Flavia

Introduction: In the pediatric population the progression of obesity-related diseases can be delayed or prevented through changes in lifestyle, including the promotion of a Mediterranean-like dietary (MD) pattern.Objective: We aimed to assess the efficacy of an educational training to MD based on gamification with respect to a conventional weight-loss treatment in obese pediatric subjects on weight decreased and cardiometabolic risk factors (GOOD-DAY Tri...

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ea0070oc3.5 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Supplementation with Bifidobacterium breve BR03 and Bifidobacterium breve B632 favoured weight loss and improved insulin metabolism in children and adolescents with obesity in the BIFI-OBESE cross-over, randomized placebo-controlled trial

Solito Arianna , Hasballa Iderina , Calgaro Matteo , Bozzi Cionci Nicole , Ricotti Roberta , Caputo Marina , Genoni Giulia , Monzani Alice , Archero Francesca , Bellone Simonetta , Bona Gianni , Agosti Emanuela , Aimaretti Gianluca , Amoruso Angela , Pane Marco , Vitulo Nicola , Di Gioia Diana , Prodam Flavia

Background: Variations in gut microbiota might impact metabolic functions like caloric intake and energy expenditure leading to body weight excess. Microbiota modulation may be a potential approach for obesity management, especially in subject characterized by specific microbial enterotypes.Objective: We aimed to assess the impact of probiotic treatment in obese children and adolescents, under diet control, on weight loss, glucose, and insulin homeostasi...

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ea0070oc4.2 | Pituitary and Neuroendocrinology | ECE2020

Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice

Agosti Emanuela , De Feudis Marilisa , Angelino Elia , Belli Roberta , Alves Teixeira Maraiza , Zaggia Ivan , Raiteri Tommaso , Scircoli Andrea , Graziani Andrea , Prodam Flavia , Sanpaolesi Maurilio , Costelli Paola , Ferraro Elisabetta , Reano Simone , Filigheddu Nicoletta

Sarcopenia, the decline in muscle mass and functionality during aging, might arise from age-associated endocrine dysfunction. Indeed, muscle wasting follows the general decline in trophic hormones and the establishment of a chronic mild inflammatory status characteristic of aging. Ghrelin is a gastric hormone peptide circulating in both acylated (AG) and unacylated (UnAG) forms that have anti-atrophic activity on skeletal muscle. AG is the endogenous ligand of the growth hormo...

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ea0073pep7.8 | Presented ePosters 7: Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Cholesterol-free ketogenic diet administration ameliorates experimental metabolic syndrome

Agosti Emanuela , Reano Simone , Provera Alessia , Gadipudi Laila Lavanya , Ramavath Naresh Naik , Colasanto Antonio , Raineri Davide , Albano Emanuele , Filigheddu Nicoletta , Arlorio Marco , Coisson Jean Daniel , Chiocchetti Annalisa , Sutti Salvatore , Prodam Flavia

Background and aimsMetabolic syndrome (MetS) is a pathologic condition characterized by abdominal obesity, insulin resistance, hypertension, and dyslipidemia. The prevalence of MetS parallels the rise of obesity rate reaching pandemic proportions due to the increased consumption of high-calories-high-fat-high-carbohydrates low-fibers diet associated with a sedentary lifestyle. MetS is associated with a plethora of comorbidities as non-alcoholic fatty liv...

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ea0073aep166 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The ecology of the microbiome in children with obesity is associated to insulin resistance anddiet composition

Ricotti Roberta , Archero Francesca , Landoni Valentina , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Solito Arianna , Antoniotti Valentina , Gamalero Elisa , Massa Nadia , Mignone Flavio , Cavaletto Maria , Agosti Emanuela , Bona Elisa , Prodam Flavia

IntroductionIn the pediatric population, the progression of obesity-related diseases can be delayed or prevented through lifestyle changes, including the promotion of a Mediterranean-like dietary (MD) pattern.ObjectiveWe aimed to evaluate the gut microbiome ecology in relation to dietary and clinical parameters in the pediatric subjects with obesity recruited at baseline in a protocol on an educational traini...

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Endocrine Abstracts

The educational training to the Mediterranean diet-like pattern is followed by improvement in cardiometabolic parameters and ecology of the microbiome in children with obesity: Preliminary results of the GOOD DAY trial

Supplementation with Bifidobacterium breve BR03 and Bifidobacterium breve B632 favoured weight loss and improved insulin metabolism in children and adolescents with obesity in the BIFI-OBESE cross-over, randomized placebo-controlled trial

Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice

Cholesterol-free ketogenic diet administration ameliorates experimental metabolic syndrome

The ecology of the microbiome in children with obesity is associated to insulin resistance anddiet composition

BiosciAbstracts